Air separation plants (ASP), working in thermodynamic cycle of average pressure, are widely used at numerous enterprises of oxygen and nitrogen production. The increase of their efficiency and safety is an actual problem. It is informed about the creation of new generation of ASP. The new schemes, constructions and equipment used in them make it possible to solve this problem. As the result, high-effective ASP for production of liquid cryoproducts have been created. The developing experience of such ASP is successfully used in the modernization of the exist plants.